Hexon protein is a major coat protein of adenoviruses. Adenoviruses capsids have three principal protein components: the hexon, the penton, and the fiber. Hexon consists of three subunits together forming two major components of different morphological symmetry. A triangular top with three towers of density is superimposed on a more bulky pseudo hexagonal base. The symmetry of the top is in accord with the trimeric nature of hexon, but that of the base derives from the molecular function, which is to provide a densely packed impenetrable protective outer layer for the virion.
Applications:
Suitable for use in ELISA and IFA. Not recommended for use with methanol-fixed cells. Other applications not tested.
Recommended Dilutions:
Optimal dilutions to be determined by the researcher.
Recommended pairs for sandwich immunoassay:
A0880-01A: Adenovirus, Type 6
A0880-03B: Adenovirus, Hexon
A0880-01E: Adenovirus, Hexon
Storage and Stability:
May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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