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Adiponectin, globular domain, Recombinant, Rat (His) (ACRP30, AdipoQ, apM1, GBP28, Adipocyte Complement Related Protein of 30kD)

Adiponectin, globular domain, Recombinant, Rat (His) (ACRP30, AdipoQ, apM1, GBP28, Adipocyte Complement Related Protein of 30kD)

Cat no: 044481

Supplier: United States Biological
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ACRP30 was identified as a novel adipocyte-specific synthesized and secreted protein with structural resemblance to complement factor C1q. Like adipsin, ACRP30 secretion is induced ~10-fold during adipocyte differentiation. Plasma levels are reduced in obese humans and low levels are associated with insulin-resistance. Treatment of db/db mice with TZD increased ACRP30 levels. Sequence: The globular domain (aa 104-244) of rat adiponectin is fused at the C-terminus to a His-tag. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Working aliquots are stable for up to 3 months when stored at -20 degrees C.
Catalogue number: 044481
Size: 50ug
Form: 0.2um filtered solution in 30mM TRIS-Cl, pH 8.5.
Purity: >90% (SDS-PAGE)
Alternative names: ACRP30, AdipoQ, apM1, GBP28, Adipocyte Complement Related Protein of 30kDa
References: Product Reference: ?Role of adiponectin receptors in endothelin-induced cellular hypertrophy in cultured cardiomyocytes and their expression in infarcted heart: D. Fujioka, et al.; Am. J. Physiol. Heart Circ. Physiol. 290, H2409 (2006) ?Statin reverses reduction of adiponectin receptor expression in infarcted heart and in TNF-alpha-treated cardiomyocytes in association with improved glucose uptake: Y. Saito, et al.; Am. J. Physiol. Heart Circ. Physiol. 293, H3490 (2007) ?

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