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Adiponectin, globular domain, Recombinant, Rat (His) (ACRP30, AdipoQ, apM1, GBP28, Adipocyte Complement Related Protein of 30kD)

Cat no: 044481


Supplier: United States Biological
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ACRP30 was identified as a novel adipocyte-specific synthesized and secreted protein with structural resemblance to complement factor C1q. Like adipsin, ACRP30 secretion is induced ~10-fold during adipocyte differentiation. Plasma levels are reduced in obese humans and low levels are associated with insulin-resistance. Treatment of db/db mice with TZD increased ACRP30 levels. Sequence: The globular domain (aa 104-244) of rat adiponectin is fused at the C-terminus to a His-tag. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Working aliquots are stable for up to 3 months when stored at -20 degrees C.
Catalogue number: 044481
Size: 50ug
Form: 0.2um filtered solution in 30mM TRIS-Cl, pH 8.5.
Purity: >90% (SDS-PAGE)
Alternative names: ACRP30, AdipoQ, apM1, GBP28, Adipocyte Complement Related Protein of 30kDa
References: Product Reference: ?Role of adiponectin receptors in endothelin-induced cellular hypertrophy in cultured cardiomyocytes and their expression in infarcted heart: D. Fujioka, et al.; Am. J. Physiol. Heart Circ. Physiol. 290, H2409 (2006) ?Statin reverses reduction of adiponectin receptor expression in infarcted heart and in TNF-alpha-treated cardiomyocytes in association with improved glucose uptake: Y. Saito, et al.; Am. J. Physiol. Heart Circ. Physiol. 293, H3490 (2007) ?

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