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Adiponectin Receptor 1 (AdipoR1, CGI-45)

Cat no: 044474

Adiponectin Receptor 1 (AdipoR1, CGI-45)

AdipoR1 is a receptor for globular and full-length adiponectin, an essential hormone secreted by adipocytes that acts as an antidiabetic. AdipoR1 is probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. It mediates increased AMPK, PPAR-alpha ligand activity, fatty acid oxidation and glucose uptake by adiponectin. It is a high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin. It is widely expressed.\n\nApplications:\nSuitable for use in Immunohistochemistry, Western Blot\n\nRecommended Dilution:\nOptimal dilutions to be determined by researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

044474

Size

100ul

Applications

IHC, WB

Hosts

Rabbit

Form

Neat serum 0.02% sodium azide.

P Type

Pab

References

Product Reference: \n?Fibrosis is associated with adiponectin resistance in chronic hepatitis C virus infection: S. Corbetta, et al.; Eur. J. Clin. Invest. (Epub ahead) (2011)\n?

Additional Info

Recognizes human adiponectin receptor 1.

Alternative Names

AdipoR1, CGI-45

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