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ADRA1C Antibody

ADRA1C Antibody

Cat no: 252025

Supplier: ABBIOTEC
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Adrenergic Receptors (ARs) are members of the 7-transmembrane domain G-protein-coupled receptor superfamily that bind the endogenous catecholamines epinephrine and norepinephrine. Pharmacological, structural, and molecular cloning data indicate significant heterogeneity within this receptor family. Nine receptor subtypes have been identified thus far including three alpha 1 AR subtypes (1A/D, 1Bovine, and 1C), three alpha 2 ARs (2A, 2Bovine, and 2C), and three beta AR subtypes (1, 2, and 3). ARs participate in either the onset or maintenance of several disease states including hypertension, cardiac dysfunction (congestive heart failure, ischemia, arrhythmias), diabetes, glaucoma, depression, and impotence. A1AR subtypes are found in numerous tissues and have been shown to be involved in the regulation of blood pressure due to changes in vascular tone and cardiac output. Effects on uterine contraction, hepatic glucose metabolism, heat shock protein 70 (HSP 70),Porcineroto-oncogene e, Xenopus/Amphibian,pression, and mitogenesis have been linked to A1AR activation.
Catalogue number: 252025
Reactivities: Human, Mouse, Rabbit, Zebrafish/Fish
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: Q6LD06
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ADRA1C.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Alpha-1c adrenergic receptor subtype; ADRA1C; ADRA1A
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