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Aggrecan Antibody

Aggrecan Antibody

Cat no: 251591

Supplier: ABBIOTEC
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Aggrecan core protein (Cartilage-specific proteoglycan core protein) is a major component of e, Xenopus/Amphibian,tracellular matri, Xenopus/Amphibian, of cartilagenous tissues. The major function of aggrecan is to resist compression in cartilage. Aggrecan binds avidly to hyaluronic acid via an N-terminal globular region. E, Xenopus/Amphibian,pression of aggrecan is restricited to cartilages in chondrocytes throughout the developing skeleton. Aggrecan contains mostly chondroitin sulfate and lesser keratan sulfate chains, N-linked and O-linked oligosaccharides. The release of aggrecan fragments from articular cartilage into the synovial fluid at all stages of human osteoarthritis is the result of cleavage by aggrecanase. Defects in aggrecan are the cause of spondyloepiphyseal dysplasia type Kimberley (SEDK) and spondyloepimetaphyseal dysplasia aggrecan type (SEMD-ACAN).
Catalogue number: 251591
Reactivities: Human, Mouse, Bovine, Chicken/Bird, Porcine, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P16112
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human aggrecan.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Aggrecan core protein; Cartilage-specific proteoglycan core protein; CSPCP; Chondroitin sulfate proteoglycan core protein 1; Chondroitin sulfate proteoglycan 1; ACAN; AGC1; CSPG1; MSK16
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