Home  >  Products  >  AGPAT6 (1-acyl-sn-glycerol-3-phosphate acyltransferase zeta, Testis spermatogenesis apoptosis-related protein 7, EC=2.3.1.51, 1-AGP acyltransferase 6, 1-AGPAT 6, Lysophosphatidic acid acyltransferase-zeta, LPAAT-zeta)
AGPAT6 (1-acyl-sn-glycerol-3-phosphate acyltransferase zeta, Testis spermatogenesis apoptosis-related protein 7, EC=2.3.1.51, 1-AGP acyltransferase 6, 1-AGPAT 6, Lysophosphatidic acid acyltransferase-zeta, LPAAT-zeta)

AGPAT6 (1-acyl-sn-glycerol-3-phosphate acyltransferase zeta, Testis spermatogenesis apoptosis-related protein 7, EC=2.3.1.51, 1-AGP acyltransferase 6, 1-AGPAT 6, Lysophosphatidic acid acyltransferase-zeta, LPAAT-zeta)

Cat no: A1059-59D

Supplier: United States Biological
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AGPAT6 is a novel glycerolipid acyltransferase of the ER, which is crucial for the production of milk fat by the mammary gland. Agpat6 deficient mice exhibit a 25% reduction in body weight and resistance to both diet-induced and genetically induced obesity. The reduced body weight is associated with increased energy expenditure, reduced triglyceride accumulation in BAT and WAT, reduced white adipocyte size, and lack of adipose tissue in the subdermal region. AGPAT6 plays a unique role in determining triglyceride content and composition in adipose tissue and liver that cannot be compensated by other members of the Agpat family. (1) Cellular Localization: Membrane Positive Control: Mouse skeletal muscle lysate Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: A1059-59D
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Western Blot
Size: 100ul
Form: Supplied as a liquid in Tris-glycine, 150mM sodium chloride, pH 7.2.
P type: Pab
Purity: Purified by peptide immunoaffinity chromatography.
Alternative names: 1-acyl-sn-glycerol-3-phosphate acyltransferase zeta, Testis spermatogenesis apoptosis-related protein 7, EC=2.3.1.51, 1-AGP acyltransferase 6, 1-AGPAT 6, Lysophosphatidic acid acyltransferase-zeta, LPAAT-zeta
References: 1. Beigneux, AP, et al. J. Lipid Res. 47: 734-744 (2006) 2. Vergnes, L., et al. J. Lipid Res. 47: 745-754 (2006)
Additional info: This antibody is specific for AGPAT6. Species Crossreactivity: Human and mouse. Other species not tested.

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