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Ah Receptor (Aryl Hydrocarbon Receptor)

Cat no: A1059-72

Ah Receptor (Aryl Hydrocarbon Receptor)

The Ah Receptor belongs to a family of proteins comprised of its dimerization partner ARNT (HIF-1 Beta) and the Drosophila proteins PER and SIM. All of these proteins share an N-terminal sequence of ~200aa termed the PAS domain. This receptor, found in a variety of tissues, binds to a specific DNA enhancer sequence and initiates transcription of the mRNA for the cytochrome P-450 (CYPIA1) gene.\n\nApplications: \nSuitable for use in ELISA, Western Blot and Gel Super Shift Assays. Other applications not tested.\n\nRecommended Dilutions:\nGel Super Shift Assays: 4ul to a 15ul final volume of EMSA sample.\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

A1059-72

Size

1ml

Applications

ELISA, WB

Hosts

Goat

Reactivities

Hum, Mouse

Form

Supplied as a liquid, sodium azide

P Type

Pab

Purity

Serum

Isotype

IgG

References

1. Chan, WK, et al. J Biol Chem. 1994 Oct 21;269(42):26464-71. 2. Poland, A, Glover, E, Bradfield, CA. Mol Pharmacol. 1991 Jan;39(1):20-6. Erratum in: Mol Pharmacol 1991 Apr;39(4):435. 3. Dabir P, et al. Circ Res. 2008 Jun 20;102(12):1558-65. Epub 2008 May 30.. 4. Fisher, M, et al. Toxicol Sci. 2004 Mar;78(1):116-24. Epub 2004 Jan 12. 5. Hayashibara, T, et al. Biochem Biophys Res Commun. 2003 Jan 3;300(1):128-34. 6. Tsuchiya, Y, et al. J Biochem. 2003 May;133(5):583-92. 7. Minsavage, GD, et al. Arch Biochem Biophys. 2003 Apr 1;412(1):95-105.

Additional Info

Recognizes Ah Receptor. Species Crossreactivity: mouse and human

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