
Supplier:
United States BiologicalCat no: 123110
AIM2 (Interferon-inducible Protein AIM2, Absent in Melanoma 2, PYHIN4)
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SPECIFICATIONS
Catalog Number
123110
Size
50ug
Applications
IF, WB
Hosts
Mouse
Reactivities
Hum, Mouse
Form
Supplied as a liquid in PBS, pH 7.2.
P Type
Pab
Purity
Purified by Protein A affinity chromatography.
Isotype
IgG
References
1.Absent in Melanoma 2 (AIM2) is an important mediator of interferon-dependent and -independent HLA-DRA and HLA-DRB gene expression in colorectal cancers. Lee J, Li L, Gretz N, Gebert J, Dihlmann S.Oncogene. 2011 Aug 1. doi: 10.1038/onc.2011.320. [Epub ahead of print] 2. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES.Nature. 2009 Mar 26;458(7237):509-13. Epub 2009 Jan 21.
Additional Info
Recognizes human AIM2.
SUPPLIER INFO
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