Home  >  Products  >  AKAP6 (A Kinase (PRKA) Anchor Protein 6, ADAP6, PRKA6, mAKAP, ADAP100, AKAP100, KIAA0311, A-Kinase Anchor Protein 100)
AKAP6 (A Kinase (PRKA) Anchor Protein 6, ADAP6, PRKA6, mAKAP, ADAP100, AKAP100, KIAA0311, A-Kinase Anchor Protein 100)

AKAP6 (A Kinase (PRKA) Anchor Protein 6, ADAP6, PRKA6, mAKAP, ADAP100, AKAP100, KIAA0311, A-Kinase Anchor Protein 100)

Cat no: A1102-81D

Supplier: United States Biological
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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:16000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: A1102-81D
Reactivities: Human, Mouse, Rat
Hosts: Goat
Applications: ELISA
Size: 100ug
Form: Supplied as a liquid in Tris-saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. McCartney S, Little BM, Langeberg LK, Scott JD. Cloning and characterization of A-kinase anchor protein 100 (AKAP100). A protein that targets A-kinase to the sarcoplasmic reticulum. J Biol Chem. 1995 Apr 21;270(16):9327-33.
Additional info: Recognizes human AKAP6. Species Crossreactivity: Mouse and rat.

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