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AKT, phosphorylated (Thr34) (Rac PKa, PKBa)

AKT, phosphorylated (Thr34) (Rac PKa, PKBa)

Cat no: A1124-01M

Supplier: United States Biological
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AKT, also known as Protein Kinase B (PKB) and Rac (Related to the A and C kinases), is a 60kDa serine/threonine kinase critical for controlling diverse cellular functions, including glucose metabolism, gene transcription, cell proliferation, and apoptosis. AKT phosphorylates a number of physiological substrates including MBP, glycogen synthetase, PKA RII subunit, and histone H1. AKT is activated in response to insulin and growth factors in a PI3-kinase dependent manner. Activation of PI3-Kinase generates phosphatidylinositol 3,4-bisphosphate which may induce the membrane translocation of AKT coincident with its phosphorylation and activation. Upon activation, AKT associates with members of the PKC family of kinases, such as PKC
Catalogue number: A1124-01M
Reactivities: Human, Rat, Rabbit
Hosts: Rabbit
Applications: Western Blot
Size: 100ul
Form: Supplied as a liquid in PBS, 1mg/ml BSA, 0.05% sodium azide, 50% gylcerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human AKT, phosphorylated at Thr34. Species Crossreactivity: rat, rabbit.

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