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Akt Substrate, 160kD (AS160, DKFZp779C0666, KIAA0603, TBC1 domain family member 4, Rab GAP)

Akt Substrate, 160kD (AS160, DKFZp779C0666, KIAA0603, TBC1 domain family member 4, Rab GAP)

Cat no: A1124-53J

Supplier: United States Biological
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S160 is a 160kD Akt serine/threonine kinase substrate that plays a critical role in regulating insulin-stimulated exocytosis of glucose transporter GLUT4. Increased in insulin treatment stimulate phophorylation of AS160 that regulates GLUT4 translocation via inactivation of the Rab GTPase function. Applications: Suitable for use in Western Blot. Other applications have not been tested. Recommended Dilutions: Western Blot: 1-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: A1124-53J
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 5mM EDTA, 0.01% thimerosal, 30% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
Alternative names: TBC1D4; AS160; DKFZp779C0666
Additional info: Recognizes human Akt Substrate. Species crossreactivity: mouse, rat

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