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Akt1, phosphorylated (Ser473) (Rac PKa, PKBa)

Cat no: A1125-03A

Akt1, phosphorylated (Ser473) (Rac PKa, PKBa)

The serine/threonine kinase Akt1 has also been described as Rac-PKa or PKBa. Rac protein kinase family members feature a pleckstrin homology (PH) domain at the amino terminus and a protein-serine/threonine kinase catalytic domain at the carboxy terminus. The PH domain (amino acids 1

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SPECIFICATIONS

Catalog Number

A1125-03A

Size

100ug

Applications

WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat, Can

Form

Supplied as a liquid in PBS containing 0.09% sodium azide.

P Type

Mab

Purity

Purified from serum-free cell culture supernatant by subsequent thiophilic adsorption and size exclusion chromatography

Isotype

IgG1,k

References

1. Cross, D.A., et al., Nature 378: 785-789, 1995. 2. James, S.R., et al., Biochem. J. 315: 709-713, 1996. 3. Alessi, D.R., et al., Curr. Biol. 8: 69-81, 1998. 4. Alessi, D.R., et al., Curr. Biol. 7: 776-789, 1997. 5. Cohen, P., et al., FEBS Lett. 410: 3-10, 1997.

Additional Info

Recognizes phosphorylated Akt1/PKBa at Ser473, Mr 60kD. Does not crossreact with Akt1/PKBa dephosphorylated at Ser473. Species Crossreactivity: Human, mouse, canine and rat.

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