Home  >  Products  >  AKT3 (DKFZP434N0250, Protein Kinase B gamma, PKB gamma, PKBG, PRKBG, RAC gamma Serine/Threonine Protein Kinase, RACPK gamma, RAC-PK-gamma, Serine Threonine Protein Kinase Akt-3, STK-2, v-AKT Murine Thymoma Viral Oncogene Homolog 3)
AKT3 (DKFZP434N0250, Protein Kinase B gamma, PKB gamma, PKBG, PRKBG, RAC gamma Serine/Threonine Protein Kinase, RACPK gamma, RAC-PK-gamma, Serine Threonine Protein Kinase Akt-3, STK-2, v-AKT Murine Thymoma Viral Oncogene Homolog 3)

AKT3 (DKFZP434N0250, Protein Kinase B gamma, PKB gamma, PKBG, PRKBG, RAC gamma Serine/Threonine Protein Kinase, RACPK gamma, RAC-PK-gamma, Serine Threonine Protein Kinase Akt-3, STK-2, v-AKT Murine Thymoma Viral Oncogene Homolog 3)

Cat no: A1125-35N

Supplier: United States Biological
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AKT3 is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: ELISA: 0.25ug/ml Western Blot: 0.5-2.5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: A1125-35N
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.09% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by Protein A afinity chromatography.
Alternative names: EC=2.7.11.1, PKB-gamma, RAC-gamma
References: 1.Xu, Z., et al., Biochem. Biophys. Res. Commun. 312(2):388-396 (2003). 2.Tiwari, G., et al., Mol. Cancer Res. 1(6):475-484 (2003). 3.Brozinick, J.T. Jr., et al., Diabetes 52(4):935-941 (2003). 4.Deregibus, M.C., et al., J. Biol. Chem. 277(28):25195-25202 (2002). 5.Brodbeck, D., et al., J. Biol. Chem. 276(31): 29550-29558 (2001).
Additional info: Recognizes human Akt3 at ~56kD. Species crossreactivity: mouse

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