Alexa Fluor(R) 488 anti-mouse CD11c

CD11c is a 150 kD glycoprotein also known as alphaX integrin, CR4, and p150. CD11c forms a alphaXbeta2 heterodimer with beta2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The alphaXbeta2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen, and CD54.

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SPECIFICATIONS

Catalog Number

117313

Size

25 microg

Applications

FC, IF, IHC

Hosts

Ham

Reactivities

Mouse

Clone

N418

Antigen

Mouse spleen dendritic cells

Gene Id

16411

Isotype

Armenian Hamster IgG

Clonality

Monoclonal

Dilutions

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ? 0.25 microg per 106 cells in 100 microl volume. It is recommended that the reagent be titrated for optimal performance for other applications. * Alexa Fluor(R) 488 has a maximum emission of 519 nm when it is excited at 488 nm.** Alexa Fluor(R) is a registered trademark of Molecular Probes, Inc. Alexa Fluor(R) dye antibody conjugates are sold under license from Molecular Probes, Inc. for research use only, except for use in combination with microarrays and high content screening, and are covered by pending and issued patents.

Storage Temp

4 C

Concentration

0.5 mg/ml

Shipping Temp

Ambient RT

Storage Buffer

The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.

Alternative Names

alphaX integrin chain, alphaXbeta2, CR4, p150, alpha integrin, alphaX integrin, alpha X integrin, aX integrin, integrin alphaX, integrin aX, integrin alpha X

Regulatory Status

RUO