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Alexa Fluor(R) 647 anti-human CD101 (BB27)

Alexa Fluor(R) 647 anti-human CD101 (BB27)

Cat no: 331009


Supplier: BioLegend
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CD101 is a type I transmembrane glycoprotein also known as V7 and P126. It is a 120 kD homodimer and member of the EWI family within the Ig superfamily. CD101 is found on monocytes, granulocytes, dendritic cells, and a subpopulation of peripheral blood T cells and activated T cells. It has been reported that CD101 expressing Tregs possess higher inhibitory function. The biological function of CD101 is still not clear, but it has been found that BB27 antibody is able to inhibit T cell proliferative responses and this inhibitory function can be overcome by high doses of IL-2. Activation of CD101 on dendritic cells is able to induce IL-10 production.
Catalogue number: 331009
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 25 tests
Clone: BB27
Gene: 9398
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 microl per million cells or 5 microl per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor(R) 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.** Alexa Fluor(R) 647 is a registered trademark of Molecular Probes, Inc. Alexa Fluor(R) 647 dye antibody conjugates are sold under license from Molecular Probes, Inc. for research use only, except for use in combination with microarrays and high content screening, and are covered by pending and issued patents.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Isotype: Mouse IgG1, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: BB27
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