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Alexa Fluor(R) 647 anti-human CD191 (CCR1)

Alexa Fluor(R) 647 anti-human CD191 (CCR1)

Cat no: 335201


Supplier: BioLegend
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CCR1 is a chemokine receptor that binds to multiple proinflammatory chemokines. CCR1 is expressed by monocytes/macrophages (≈87% of the peripheral blood), natural killer cells, T cells, DC, monocytes, basophils, eosinophils, osteoclasts, platelets, bone marrow stromal cells, human airway smooth muscle cells (ASMC), and increases in allograft recipients in peripheral blood before rejection (1-3). CCR1 plays a key role in T cell-mediated liver diseases, animal models of pulmonary fibrosis, and might be involved in asthma (1, 4). In addition, CCR1 and CCL23 promoted the chemotactic migration and differentiation of endothelial cells, and neovascularization in the chick chorioallantoic membrane (5).
Catalogue number: 335201
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 25 tests
Clone: TG4/CCR1
Gene: 1230
Dilutions: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 microl per million cells or 5 microl per 100 microl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor(R) 647 has a maximum emission of 668 nm when it is excited at 633nm / 635nm.** Alexa Fluor(R) is a registered trademark of Molecular Probes, Inc. Alexa Fluor(R) dye antibody conjugates are sold under license from Molecular Probes, Inc. for research use only, except for use in combination with microarrays and high content screening, and are covered by pending and issued patents.
Storage buffer: The antibody solution should be stored undiluted at 4C and protected from prolonged exposure to light. Do not freeze.
Antigen: Human CCR1 transfectants
Isotype: Mouse IgG2b, kappa
Clonality: Monoclonal
Regulatory status: RUO
Shipping temp: Ambient RT
Storage temp: 4 C
Alternative names: CCR1, CKR-1, CMKBR1
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