ALK (W1503) pAb

LTK, ALK and Ros have been identified as receptor tyrosine kinases having sequence similarity to the Insulin receptor subfamily of kinases. LTK, leukocyte tyrosine kinase, is expressed in murine B lymphocyte precursors and has also been found in forebrain neurons. ALK, anaplastic lymphoma kinase, is normally highly expressed specifically in the nervous system. A truncated form containing the catalytic domain of ALK is expressed as the result of a translocation occuring in many non-Hodgkin's lymphomas. The c-Ros gene was originally identified in mutant form as an oncogene. Ros is normally expressed in a small number of epithelial cell types and may play a role in epithelial development.

Prices direct from Bioworld Technology, Inc.

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

BS3243

Size

100ug/100ul

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids 1470-1523 of Human ALK.

Species

ALK (W1503) pAb detects endogenous levels of ALK protein.

Dilutions

WB: 1:500~1:1000

Swiss Prot

Q9UM73

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul