Alpha-4 Integrin Antibody

Cat no: 251867

Supplier: ABBIOTEC

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Description
Additional Information

Integrin alpha-4 (CD49d) is a receptor for fibronectin. Integrin alpha-4 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-4 is also a receptor for VCAM1, recognizing the sequence Q-I-D-S in VCAM1, and a receptor for MADCAM1, recognizing the sequence L-D-T in MADCAM1. On activated endothelial cells, integrin alpha-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines, and also participates in cytolytic T-cell interactions with target cells.

Catalogue number:	251867
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunocytochemistry, Immunohistochemistry
Size:	0.1 mg
Accession:	P13612
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human integrin alpha-4.
Format:	Each vial contains 0.1 mg IgG in 0.5 ml (0.2 mg/ml) of PBS pH7.4, 50% glycerol. Antibody was purified by immunogen-affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Integrin alpha-4; Integrin alpha-IV; VLA-4 subunit alpha; CD49 antigen-like family member D; CD49d; ITGA4; CD49D