ALS2CR2 (CT) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein, CALS-21, ILP-interacting protein, ILPIP, ILPIPA, MGC102916, PAPK, PRO1038, Pseudokinase ALS2CR2, Serine/threonine-protein kinase ALS2CR2, STE20-related kinase adapt

ILPIP plays an essential role in G1 cell cycle arrest. ILPIP also activates JNK family members, particularly in the presence of XIAP and interacts with TAK1 and tumor necrosis factor receptor-associated factor 6. ILPIP is highly expressed in heart, skeletal muscle, testis, liver and colon.\n\nApplications:\nSuitable for use in Western Blot, Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 0.5-2ug/ml\nImmunohistochemistry (Paraffin): 5ug/ml\nOptimal dilutions to be determined by the researcher.\n\nRecommended Secondary Antibodies:\nGoat Anti Rabbit IgG (H&L) HRP\nSheep Anti Rabbit IgG Biotin\nGoat Anti Rabbit IgG (Fc) FITC, HRP\nGoat Anti Rabbit IgG (H&L) HRP\nSheep Anti Rabbit IgG FITC\nSheep Anti Rabbit IgG RPE\nSheep Anti Rabbit IgG DyLight(TM)488, DyLight(TM)549, DyLight(TM)649\nSheep Anti Rabbit IgG HRP\n\nImmunohistochemistry Positive Control Tissue: \nHuman heart\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.\n\n\n\n\n

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

A1363-10B

Size

100ug

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

1. Sanna, M.G. et al. (2002) ILPIP, a novel anti-apoptotic protein that enhances XIAP-mediated activation of JNK1 and protection against apoptosis. J. Biol. Chem. 277: 30454 - 30462

Additional Info

Recognizes the CT of human ILP-interacting protein (ILPIP), a pseudokinase which activates serine/threonine-protein kinase 11 and relocates it from the nucleus to the cytoplasm.