Amodiaquine is an antimalarial drug with effects very similar to those of chloroquine. Amodiaquine has been widely used to treat malaria. Due to reports of fatal adverse drug reactions, discontinuation or modification of its use has been suggested. Amodiaquine is a hapten of molecular weight 267.3 g/mol. This antibody is specific for the non-quinoline sidechain of amodiaquine. The antibody can be used for quantitation of amodiaquine in human serum or plasma with a detection limit close to 2 ng/ml.