Home  >  Products  >  AMP Activated Protein Kinase alpha1 (AMPK Subunit alpha-1, AMPK a1, AMPKa1, 5'-AMP-activated Protein Kinase Catalytic Subunit alpha-1, AMPK1, AMPK, MGC33776, MGC57364, PRKAA1)
AMP Activated Protein Kinase alpha1 (AMPK Subunit alpha-1, AMPK a1, AMPKa1, 5'-AMP-activated Protein Kinase Catalytic Subunit alpha-1, AMPK1, AMPK, MGC33776, MGC57364, PRKAA1)

AMP Activated Protein Kinase alpha1 (AMPK Subunit alpha-1, AMPK a1, AMPKa1, 5'-AMP-activated Protein Kinase Catalytic Subunit alpha-1, AMPK1, AMPK, MGC33776, MGC57364, PRKAA1)

Cat no: A1475-01D

Supplier: United States Biological
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AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl- CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. It appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. AMPK alpha1, a member of the Ser/Thr protein kinase family, is a catalytic subunit of AMPK. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: ELISA: 0.25ug/ml Western Blot: 0.5-2.5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: A1475-01D
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.09% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by Protein G afinity chromatography.
Alternative names: EC=2.7.11.1, Protein Kinase AMP-activated alpha 1 Catalytic Subunit
References: 1. Zhang, Q.H., et al., Genome Res. 10(10):1546-1560 (2000). 2. Stapleton, D., et al., J. Biol. Chem. 271(2):611-614 (1996).
Additional info: Recognizes human AMPKa1. Species crssreactivity: mouse.

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