Home  >  Products  >  AMP Activated Protein Kinase alpha1 (AMPK Subunit alpha-1, AMPK a1, AMPKa1, 5'-AMP-activated Protein Kinase Catalytic Subunit alpha-1, AMPK1, AMPK, MGC33776, MGC57364, PRKAA1)
AMP Activated Protein Kinase alpha1 (AMPK Subunit alpha-1, AMPK a1, AMPKa1, 5'-AMP-activated Protein Kinase Catalytic Subunit alpha-1, AMPK1, AMPK, MGC33776, MGC57364, PRKAA1)

AMP Activated Protein Kinase alpha1 (AMPK Subunit alpha-1, AMPK a1, AMPKa1, 5'-AMP-activated Protein Kinase Catalytic Subunit alpha-1, AMPK1, AMPK, MGC33776, MGC57364, PRKAA1)

Cat no: A1475-01E

Supplier: United States Biological
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AMPK1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime- AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: ELISA: 0.25ug/ml Western Blot: 0.5-2.5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: A1475-01E
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.09% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by ammonium sulfate precipitation.
Alternative names: EC=2.7.11.1, Protein Kinase AMP-activated alpha 1 Catalytic Subunit
References: Stapleton D., Mitchelhill K.I.J. Biol. Chem. 271:611-614(1996) Lizcano J.M., Goeransson O.EMBO J. 23:833-843(2004) Hawley S.A., Pan D.A.Cell Metab. 2:9-19(2005)
Additional info: Recognizes human AMPK1.

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