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Amyloid Beta, 1-40, 42 (CT) (Amyloid A4)

Cat no: A2275-59G


Supplier: United States Biological
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Alzheimers disease (AD) is characterized by the presence of senile plaques in the brain and blood vessel walls. Amyloid Beta A4 (Ab4) protein has been found to be the principal constituent of senile plaques of ADs patients. The amyloid beta-protein precursor (APP) is proteolytically cleaved to generate the 4kD Ab4 protein. Two variants of Ab4 can be detected; Ab-40 short-tailed and Ab-42 long-tailed. Applications: Suitable for use in ELISA, Western Blot, and Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 0.05ug/ml Western Blot: 1ug/ml Immunocytochemistry: 0.1-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: A2275-59G
Hosts: Mouse
Applications: ELISA, Immunocytochemistry, Western Blot
Size: 100ug
Form: Supplied as a lyophilized powder in 2X PBS, PEG, sucrose, 0.1% sodium azide. Reconstitute with 1ml dH2O.
P type: Mab
Isotype: IgG1
Purity: Purified by thiophilic adsorption and size exclusion chromatography.
Additional info: Recognizes the C-termini of both beta Amyloid 1-40 and 1-42

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