Amyloid Beta, 1-40 (CT) (Amyloid A4)

Cat no: A2275-59D

Supplier: United States Biological

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Description
Additional Information

Alzheimers disease (AD) is characterized by the presence of senile plaques in the brain and blood vessel walls. Amyloid Beta A4 (Ab4) protein has been found to be the principal constituent of senile plaques of ADs patients. The amyloid beta-protein precursor (APP) is proteolytically cleaved to generate the 4kD Ab4 protein. Two variants of Ab4 can be detected; Ab-40 short-tailed and Ab-42 long-tailed. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:500-1:50,000 Western Blot: 1:100-1:1,000 Immunohistochemistry (paraffin): 1:100-1:250 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	A2275-59D
Reactivities:	Human
Hosts:	Mouse
Applications:	ELISA, Immunohistochemistry, Western Blot
Size:	200ul
Form:	Supplied as a liquid in PBS. No preservative added.
P type:	Mab
Isotype:	IgG1
Purity:	Purified by Protein G affinity chromatography.
References:	1. Parvathy, S., et al., (2001),
Additional info:	Recognizes the C-terminus of human beta amyloid, specific for the isoform ending at the 40th amino acid.

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Amyloid Beta, 1-40 (CT) (Amyloid A4)

Cat no: A2275-59D

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