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Amyloid Precursor Protein (APP, Amyloid beta (A4) Precursor Protein)

Amyloid Precursor Protein (APP, Amyloid beta (A4) Precursor Protein)

Cat no: A2275-69A

Supplier: United States Biological
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Alzheimer's disease, the most common cause of dementia in the elderly, exists in both familial and sporadic forms. Genetic studies have identified three genes; beta-amyloid precursor protein (APP), Presenilin-1 and Presenilin-2 which, when mutated, can cause familial forms of Alzheimer's disease. APP and APP-like proteins are transmembrane glycoproteins with a similar modular domain structure. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Immunohistochemistry: 1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: A2275-69A
Reactivities: Human, Mouse, Rat, Non-Human Primate
Hosts: Rabbit
Applications: ELISA, Immunoprecipitation
Size: 100ul
Form: Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 100ug BSA and 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by Protein A and peptide affinity chromatography.
Alternative names: A4, AAA, ABETA, ABPP, AD1, Alzheimer disease amyloid protein, amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease), Amyloid beta A4 protein precursor, APPI, Cerebral vascular amyloid peptide, CTFgamma, CVAP, PN2, PN-II, PreA4, Protease nexin-II
Additional info: Recognizes human APP. Species Crossreactivity: Monkey, mouse and rat.

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