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Amyloid Precursor Protein, CT (APP, Amyloid beta (A4) Precursor Protein)

Amyloid Precursor Protein, CT (APP, Amyloid beta (A4) Precursor Protein)

Cat no: A2275-69Y

Supplier: United States Biological
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The amyloid precursor protein (APP) is a large membrane protein whose C-terminus projects into the extracellular space. In Alzheimer's disease this protein is broken down, and releases the 42 AA beta amyloid protein that is found in senile plaques and vessels. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:500-1:2500 Western Blot: 1:100-1:400 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: A2275-69Y
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 1ml
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by ammonium sulfate precipitation.
Alternative names: A4, AAA, ABETA, ABPP, AD1, Alzheimer Disease Amyloid Protein, Amyloid beta (A4) Precursor Protein (Peptidase Nexin-II, Alzheimer Disease), Amyloid beta A4 Protein Precursor, APPI, Cerebral Vascular Amyloid Peptide, CTFgamma, CVAP, PN2, PN-II, PreA4, Protease Nexin-II
Additional info: Recognizes human Amyloid Precursor Protein (C-terminal). Reacts with the unconjugated immunizing peptide in ELISA and the amyloid precurser holoprotein in western blots.

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