Cell-permeable. A potent, non-competitive inhibitor of p300 and PCAF (p300/CBP-associated factor) histone acetyltransferase (HAT) activities (IC50~8.5uM and ~5uM, respectively. Inhibits SUMOylation of RanGAP1-C2 with an IC50=2.2uM.
Solubility:
DMSO or EtOH
Molecular Weight:
~348.52
Catalogue number:
A3870-05
Size:
5mg
Form:
Supplied as a white to off-white solid.
Purity:
~95% (
References:
1. Sun, Y., et al. (2006). FEBS Lett. 580, 4353-4356.