Androgen receptor Antibody

Cat no: 252078

Supplier: ABBIOTEC

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Description
Additional Information

Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene e, Xenopus/Amphibian,pression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3. The androgen receptor binds DNA as a homodimer. The androgen receptor is part of a ternary comple, Xenopus/Amphibian, containing AR, EFCAB6/DJBP and PARK7. The androgen receptor interacts with HIPK3 and NR0B2 in the presence of androgen. The ligand binding domain interacts with MYST2/HBO1 in the presence of dihydrotestosterone. Defects in the androgen receptor are the cause of spinal and bulbar muscular atrophy , Xenopus/Amphibian,-linked type 1 (SMA, Xenopus/Amphibian,1), also known as Kennedy disease.

Catalogue number:	252078
Reactivities:	Human, Mouse, Rabbit
Applications:	Western Blot
Size:	0.1 mg
Accession:	P10275
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human androgen receptor.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4; AR; DHTR; NR3C4