Andrographolide

Cat no: 002691

Supplier: United States Biological

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Andrographolide is a labdane diterpenoid. Andrographolide is the main bioactive component isolated from the medicinal plant Andrographis paniculata. Andrographolide showed significant antihepatotoxic action in P. berghei K173- induced hepatic damage in M. natalensis. Andrographolide inhibits tumor necrosis factor-a (TNF-a)-induced intercellular adhesion mol.-1 (ICAM-1) expression and adhesion of HL-60 cells onto human umbilical vein endothelial cells (HUVEC), which are associated with inflammatory diseases. These findings suggest that Andrographolide may have potential as a cardiovascular-protective agent. Form: White Solid Melting Point: 232-235 degrees C Solubility: DMSO

Catalogue number:	002691
Size:	500mg
Form:	White Solid
Alternative names:	(3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone; [1R-[1a[E(S*)],4ab,5a,6a,8aa]]-3-[2-[Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone; 3a,14,15,18-Tetrahydroxy-5b,9bH,10a-labda-8(20),12-dien-16-oic Acid g-Lactone; Andrographis; Andrographolid
References:	Chander, R. et al.: Int. J. Pharmacog., 33, 135 (1995); Chen, H.-W. et al.: J. Nat. Prod., 74, 2408 (2011); J. Agric. Food Chem., 59, 5263 (2011);

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Andrographolide

Cat no: 002691

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