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ANG pAb

ANG pAb

Cat no: BS6523


Supplier: Bioworld Technology, Inc.
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Angiogenesis is defined as the process of neovascularization and formation of new blood vessels from the established micro-circulation. Angiogenin (ANG or ANG I) is a non-glycosylated polypeptide, 123 amino acids in length, whose function is central to this process. ANG I shows a high degree of homology with known ribonucleases such as pancreatic ribonuclease A, and the capacity of ANG I to induce blood vessel growth is critically dependent on its ribonucleolytic activity. ANG I is thought to be involved in the development of solid tumors, and ANG I antagonists are capable of inhibiting tumor growth. By a poorly understood mechanism, ANG I is endocytosed by subconfluent endothelial cells and translocated to the nucleus where it accumulates in the nucleolus. The ANG I receptor has not yet been identified.
Catalogue number: BS6523
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P03950
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human ANG.
Species: ANG pAb detects endogenous levels of ANG protein.
Molecular weight: ~ 17 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: ALS9; HEL168; MGC22466; MGC71966; RNASE4; RNASE5;
Additional info: For research use only, not for use in diagnostic procedure.

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