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Angiostatin

Angiostatin

Cat no: A2294-07A

Supplier: United States Biological
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Angiostatin is a proteolytic fragment that comprises the first four kringle domains of the ~85kD plasminogen. Angiostatin reduces endothelial cell proliferation and acts as an potent inhibitor of angiogenesis and tumor growth. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 2ug/ml. Detects a 50kD protein representing recombinant human angiostatin. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: A2294-07A
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 1mg/ml BSA, 0.05% sodium azide
P type: Pab
Isotype: IgG
Purity: Purified
References: 1. Sim BK et al. Angiostatin and endostatin: endogenous inhibitors of tumor growth. Cancer Metastasis Rev 19:181-90 (2000). 2. Drixler TA et al. Angiogenesis and surgery: from mice to man. Eur J Surg 166:435-46 (2000).
Additional info: Recognizes recombinant mouse angiostatin. Species crossreactivity: human

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