Home  >  Products  >  Angiotensin Converting Enzyme (ACE, Angiotensin I Converting Enzyme (Peptidyl-dipeptidase A) 1, ACE1, CD143, Dipeptidyl Carboxypeptidase I, DCP1, DCP, Kininase II, MGC26566, MVCD3) (Biotin)
Angiotensin Converting Enzyme (ACE, Angiotensin I Converting Enzyme (Peptidyl-dipeptidase A) 1, ACE1, CD143, Dipeptidyl Carboxypeptidase I, DCP1, DCP, Kininase II, MGC26566, MVCD3) (Biotin)

Angiotensin Converting Enzyme (ACE, Angiotensin I Converting Enzyme (Peptidyl-dipeptidase A) 1, ACE1, CD143, Dipeptidyl Carboxypeptidase I, DCP1, DCP, Kininase II, MGC26566, MVCD3) (Biotin)

Cat no: A2294-98B

Supplier: United States Biological
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CD143 is also known as angiotensin-converting enzyme (ACE). CD143 exists in two forms, a 170kD somatic form and a 90kD germinal form. The somatic form is expressed by endothelial cells (especially those of arterioles and lung capillaries), epithelial cells (especially in proximal renal tubules and in the small intestine), by some neuronal cells and variably on some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 10ul labels of a neat-1:10 working dilution to 10e6 cells in 100ul. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: A2294-98B
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Conjugates: Biotin
Size: 100ug
Form: Supplied as a liquid in 0.09% sodium azide, 1.0% BSA.
P type: Mab
Isotype: IgG1
Purity: Purified
Alternative names: Angiotensin-converting Enzyme, Soluble Form, EC=3.4.15.1, EC=3.2.1.-
References: 1. Danilov, S.M. et al. (1994) Structure - funstion analysis of angiotensin-converting enzyme using monoclonal antibodies. Selective inhibition of N-domain active center. J. Biol. Chem. 269: 26806-26814. 2. Metzger, R. et al. (2000) CD143 in the development of atherosclerosis. Atherosclerosis 150: 21-31.
Additional info: Recognizes human CD143 and active ACE binding to an N-terminal domain epitope different to that recognized by A2295-01D, A2295-02B.

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