Ankyrin Repeat Domain 28 (ANKRD28, ANKRD-28, PITK, Phosphatase Interactor Targeting K Protein)

Cat no: A2295-19L1

Supplier: United States Biological

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Additional Information

PITK was previously identified as a novel PP1 targeting subunit implicated in modulating the phosphorylation of the transcriptional regulator heterogeneous nuclear ribonucleoprotein K (hnRNP K). Through the phosphorylation of PITK at S1013 and S1017 (residues that flank or reside within a PP1C-binding motif), the binding of the PP1 catalytic subunit to PITK, and subsequently the activity of the holoenzyme, are discretely controlled. Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	A2295-19L1
Reactivities:	Human
Hosts:	Rabbit
Applications:	Immunoprecipitation, Western Blot
Size:	100ug
Form:	Tris-citrate/phosphate buffer, pH 7 to 8
P type:	Pab
Purity:	Purified by immunoaffinity chromatography.
Additional info:	Species Crossreactivity: Human. Other species not tested.

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Ankyrin Repeat Domain 28 (ANKRD28, ANKRD-28, PITK, Phosphatase Interactor Targeting K Protein)

Cat no: A2295-19L1

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