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Annexin A2 (Annexin II, ANX2, ANXA2, Calpactin 1 Heavy Chain, Lipocortin 2, p36, Placental Anticoagulant Protein IV, PAP-IV)

Cat no: A2295-23G

Annexin A2 (Annexin II, ANX2, ANXA2, Calpactin 1 Heavy Chain, Lipocortin 2, p36, Placental Anticoagulant Protein IV, PAP-IV)

The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin II is a calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.\n\nApplications: \nSuitable for use in ELISA, Immunoprecipitation, Western Blot and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilutions:\nImmunohistochemistry: Frozen sections\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

A2295-23G

Size

50ug

Applications

ELISA, IHC, IP, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. No preservative added.

P Type

Mab

Purity

Purified

Isotype

IgG2a

Additional Info

Recognizes human Annexin II.

Alternative Names

ANX2L4, Arylsulfatase B, CAL1H, Calpactin I heavy polypeptide (p36), Chromobindin 8, LIP2, Lipocortin II, LPC2, LPC2D

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