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Anti-4-Hydroxynonenal monoclonal antibody, clone IOFK-3

Anti-4-Hydroxynonenal monoclonal antibody, clone IOFK-3

Cat no: DMAB15631

Supplier: Creative Diagnostics
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Mouse anti-4-Hydroxynonenal monoclonal antibody for WB, IHC. 4-Hydroxynonenal, or 4-hydroxy-2-nonenal or 4-HNE or HNE, (C9H16O2), is an alpha,beta-unsaturated hydroxyalkenal which is produced by lipid peroxidation in cells. 4-HNE is the primary alpha,beta-unsaturated hydroxyalkenal formed in this process. 4-HNE has4reactive groups: an aldehyde, a double-bond at carbon 2, and a hydroxy group at carbon 4. It is found throughout animal tissues, and in higher quantities during oxidative stress due to the increase in the lipid peroxidation chain reaction, due to the increase in stress events. 4-HNE has been hypothesized by several researchers to play a key role in cell signal transduction, in a variety of pathways from cell cycle events to cellular adhesion.
Catalogue number: DMAB15631
Hosts: Mouse
Conjugates: Unconjugated
Clone: IOFK-3
Target: HNE
Clonality: Monoclonal
Storage temp: Store at 4°C on dry atmosphere.After reconstitution with deionized water, store at -20°C or lower.Aliquot to avoid repeated freezing and thawing.

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