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Anti-5-hydroxymethylcytosine monoclonal antibody, clone BC4/74.4

Anti-5-hydroxymethylcytosine monoclonal antibody, clone BC4/74.4

Cat no: DMABT-H21877

Supplier: Creative Diagnostics
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Rat anti-5-hydroxymethylcytosine monoclonal antibody for Dot, ICC. 5-Hydroxymethylcytosine is a DNA pyrimidine nitrogen base. It is formed from the DNA base cytosine by adding a methyl group and then a hydroxy group. It is important in epigenetics, because the hydroxymethyl group on the cytosine can possibly switch a gene on and off. It was first seen in bacteriophages in 1952. However, in 2009 it was found to be abundant in human and mouse brains, as well as in embryonic stem cells. In mammals, it can be generated by oxidation of 5-methylcytosine, a reaction mediated by the Tet family of enzymes. Its molecular formula is C5H7N3O2.
Catalogue number: DMABT-H21877
Hosts: Rat
Conjugates: Unconjugated
Clone: BC4/74.4
Target: 5-hydroxymethylcytosine
Isotype: IgG2a
Clonality: Monoclonal
Storage temp: Stable for2year at 2-8 °C from date of receipt.

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