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Anti-ABCB11 polyclonal antibody

Cat no: CABT-B8966

Anti-ABCB11 polyclonal antibody

Rabbit Anti-Human ABCB11 polyclonal antibody for WB. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.

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SPECIFICATIONS

Catalog Number

CABT-B8966

Hosts

Rabbit

Reactivities

Hum, Mouse

Target

ABCB11

Gene Id

8647

Isotype

IgG

Clonality

polyclonal

Storage Temp

Store at -20В°C. Avoid freeze / thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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