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Anti-ACTN4 monoclonal antibody, clone SN398

Cat no: CABT-BL8477

Anti-ACTN4 monoclonal antibody, clone SN398

Rabbit Anti-Human ACTN4 monoclonal antibody for IHC,WB. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008]

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SPECIFICATIONS

Catalog Number

CABT-BL8477

Hosts

Rabbit

Reactivities

Hum

Clone

SN398

Target

ACTN4

Gene Id

81

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Stable for 1 Year at -20.0В°C from date of receipt

SUPPLIER INFO

Creative Diagnostics

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