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Anti-Amyloid Beta monoclonal antibody, clone NPBC-3

Cat no: CABT-B019

Anti-Amyloid Beta monoclonal antibody, clone NPBC-3

Mouse Anti-Amyloid Beta monoclonal antibody for WB, ELISA, IF, IHC, IP. Amyloid-beta is the main component of amyloid plaques (deposits found in the brains of patients with Alzheimers disease). Similar plaques appear in some variants of Lewy body dementia and in inclusion body myositis, while amyloid-beta can also form the aggregates that coat cerebral blood vessels in cerebral amyloid angiopathy. The plaques are composed of a tangle of regularly ordered fibrillar aggregates called amyloid fibers, a protein fold shared by other peptides such as the prions associated with protein misfolding diseases. Recent research suggests that soluble oligomeric forms of the peptide may be causative agents in the development of Alzheimers disease. A number of genetic, cell biology, biochemical and animal studies support the concept that amyloid-beta plays a central role in the development of Alzheimer's disease pathology.

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SPECIFICATIONS

Catalog Number

CABT-B019

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse, Rat

Clone

NPBC-3

Target

Beta-APP

Clonality

Monoclonal

Storage Temp

Long-term storage -20В°C; Short-term storage 4В°C

SUPPLIER INFO

Creative Diagnostics

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