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Anti-ASXL1 (C-terminal) polyclonal antibody

Anti-ASXL1 (C-terminal) polyclonal antibody

Cat no: CABT-BL350

Supplier: Creative Diagnostics
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Rabbit Anti-Human ASXL1 polyclonal antibody for WB, ELISA. This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants.
Catalogue number: CABT-BL350
Reactivities: Human
Hosts: Rabbit
Applications: ELISA
Conjugates: Unconjugated
Gene: 171023
Target: ASXL1
Isotype: IgG
Clonality: Polyclonal
Storage temp: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

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