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Anti-BAG3 (C-terminal) polyclonal antibody

Cat no: CABT-B411

Anti-BAG3 (C-terminal) polyclonal antibody

Rabbit Anti-Human BAG3 polyclonal antibody for IHC-P, WB, IB, IS. BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

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SPECIFICATIONS

Catalog Number

CABT-B411

Hosts

Rabbit

Reactivities

Hum, Mouse

Conjugates

Unconj

Target

BAG3

Isotype

IgG

Clonality

polyclonal

Storage Temp

Keep as concentrated solution. Aliquot and store at -20В°C or below. Avoid multiple freeze-thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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