Anti-BDNF monoclonal antibody, clone 37141

Mouse Anti-human BDNF monoclonal antibody for WB. Brain-derived neurotrophic factor (BDNF) is a member of the NGF family of neurotrophic factors that are required for the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous system. The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT-3, and NT-4/5. These secreted cytokines are synthesized as prepropeptides that are proteolytically processed to generate the mature proteins. All neurotrophins have six conserved cysteine residues that are involved in the formation of three disulfide bonds and all share approximately 55% sequence identity at the amino acid level. Similarly to NGF, bioactive BDNF is predicted to be a non-covalently linked homodimer.

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SPECIFICATIONS

Catalog Number

CABT-B4843

Hosts

Mouse

Clone

37141

Target

BDNF

Gene Id

627

Isotype

IgG2a

Clonality

Monoclonal

Storage Temp

12 months from date of receipt, -20 to -70В°C as supplied.<br/>1 month, 2 to 8В°C under sterile conditions after reconstitution.<br/>6 months, -20 to -70В°C under sterile conditions after reconstitution.