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Anti-BRCA1 (aa 1-50) polyclonal antibody

Anti-BRCA1 (aa 1-50) polyclonal antibody

Cat no: CABT-BL458

Supplier: Creative Diagnostics
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Rabbit Anti-Human BRCA1 polyclonal antibody for WB, IHC-P. Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq, Dec 2008]
Catalogue number: CABT-BL458
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Gene: 672
Target: BRCA2
Isotype: IgG
Clonality: Polyclonal
Storage temp: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

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