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Anti-CAD monoclonal antibody, clone FQ822Z

Anti-CAD monoclonal antibody, clone FQ822Z

Cat no: CABT-BL825

Supplier: Creative Diagnostics
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Rabbit Anti-Human CAD monoclonal antibody for ICC/IF, IHC-P, WB. Carbamoyl phosphate synthetase-aspartate carbamoyltransferase-dihydroorotase (CAD) is a multifunctional protein that initiates and regulates mammalian de novo pyrimidine biosynthesis. This trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis is the rate-limiting step in the de novo pyrimidine synthetic pathway. Although most of the CAD protein in the cell is cytosolic, phosphorylation at threonine 456 localizes the protein to the nucleus. While MAPK and EGF phosphorylate CAD at threonine 456, MAPK and c-myc have been found to induce over-expression of CAD.
Catalogue number: CABT-BL825
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Clone: FQ822Z
Gene: 790
Target: DFFB
Isotype: IgG
Clonality: Monoclonal
Storage temp: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

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