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Anti-CAMLG (aa 36-85) polyclonal antibody

Anti-CAMLG (aa 36-85) polyclonal antibody

Cat no: CABT-BL4296

Supplier: Creative Diagnostics
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Rabbit Anti-Human CAMLG (aa 36-85) polyclonal antibody for WB. The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008]
Catalogue number: CABT-BL4296
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Gene: 819
Target: CAMLG
Isotype: IgG
Clonality: Polyclonal
Storage temp: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

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