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Anti-Cathepsin B monoclonal antibody, clone 2Q48

Cat no: CABT-B9014

Anti-Cathepsin B monoclonal antibody, clone 2Q48

Mouse Anti-Human Cathepsin B monoclonal antibody for WB. The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.

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SPECIFICATIONS

Catalog Number

CABT-B9014

Hosts

Mouse

Reactivities

Hum

Clone

2Q47

Target

CTSB

Gene Id

1508

Isotype

IgG1

Clonality

Monoclonal

Storage Temp

Keep as concentrated solution. Aliquot and store at -20В°C or below. Avoid multiple freeze-thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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