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Anti-CCR10 (aa 9-31) polyclonal antibody

Cat no: CABT-BL4322

Anti-CCR10 (aa 9-31) polyclonal antibody

Goat Anti-Human CCR10 (aa 9-31) polyclonal antibody for WB, ELISA, ICC, FC, IHC-P. Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]

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SPECIFICATIONS

Catalog Number

CABT-BL4322

Applications

ELISA

Hosts

Goat

Reactivities

Hum, Mouse

Conjugates

Unconj

Target

CCR10

Gene Id

2826

Isotype

IgG

Clonality

Polyclonal

Storage Temp

Shipped at 4В°C. Upon delivery aliquot and store at -20В°C or -80В°C. Avoid repeated freeze/thaw cycles.

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