Anti-CD68 monoclonal antibody, clone FE2 [Biotin]

Cat no: DMABT-46625MR

Supplier: Creative Diagnostics

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Mouse anti-Rat CD68 monoclonal antibody for FC. CD68 is a 110 kDa highly glycosylated lysosomal membrane protein. The CD68 protein belongs to a family of lysosomal glycoproteins/plasma membrane shuttling proteins that play a role in endocytosis and/or lysosomal trafficking. Unlike many other CD leucocyte antigens, the CD68 molecule is antigenically very heterogeneous, and different antibodies to CD68 show different cellular reactivities.CD68 is expressed strongly in cytoplasmic granules, and weakly on the surface of macrophages, monocytes, neutrophils, basophils and NK-cells. CD68 is also found in neoplastic cells of myeloid background. Additionally, CD68 is expressed by approximately 40% of peripheral blood Bcells and is weakly expressed in 50% of B cell type acute lymphoblastic leukaemia cells. CD68 can also be found in the cytoplasm of non-haematopoietic tissues, especially the liver, glomeruli and renal tubules.

Catalogue number:	DMABT-46625MR
Reactivities:	Rat, Bovine
Hosts:	Mouse
Conjugates:	Biotin
Clone:	FE2
Gene:	968
Target:	CD68
Isotype:	IgG1
Clonality:	Monoclonal
Storage temp:	Store at +4 oC or at -20 oC if preferred.This product should be stored undiluted.Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

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Anti-CD68 monoclonal antibody, clone FE2 [Biotin]

Cat no: DMABT-46625MR

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