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anti-Chemokine (C-C Motif) Ligand 20 (CCL20) antibody (Biotin)

Cat no: ABIN1043793

anti-Chemokine (C-C Motif) Ligand 20 (CCL20) antibody (Biotin)

anti-Chemokine (C-C Motif) Ligand 20 (CCL20) antibody (Biotin): MIP-3alpha (also known as C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1) is a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. MIP-3alpha inhibits proliferation of myeloid progenitors in colony formation assays and may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. MIP-3alpha also possesses antibacterial activity against E.coli and S.aureus. MIP-3alpha is a secreted protein that is expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of expression are also seen in thymus, prostate, testis, small intestine and colon. C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.

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SPECIFICATIONS

Catalog Number

ABIN1043793

Size

100 micro g

Applications

WB

Hosts

Mouse

Reactivities

Hum

Conjugates

Biotin

Clone

3N2D9

Antigen

MIP-3alpha

Gene Id

6364

Isotype

IgG

Accession

P78556

Clonality

Monoclonal

Concentration

1.0 mg/mL

Entrez Gene Id

6364

SUPPLIER INFO

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