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Anti-COL4A1 monoclonal antibody, clone 688333

Cat no: CABT-B8968

Anti-COL4A1 monoclonal antibody, clone 688333

Mouse Anti-Mouse COL4A1 monoclonal antibody for ICC. This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants.

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SPECIFICATIONS

Catalog Number

CABT-B8968

Hosts

Mouse

Reactivities

Hum

Clone

688333

Target

COL4A1

Gene Id

1282

Isotype

IgG1

Clonality

monoclonal

Storage Temp

Store at -20В°C. Avoid freeze-thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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